George Lopez will exit the sitcom world once again as NBC canceled “Lopez vs. Lopez” after three seasons

NBC cut the struggling sitcom on Friday, just days before the network was scheduled to pitch the company’s future programming to advertisers,

The jokester, who previously led the Emmy-award-winning “George Lopez” show from 2002 to 2007, said he was “grateful and thankful” for the show as he reposted a video of his daughter and co-star Mayan Lopez, 29, reacting to the cancellation.

The video was captioned “When NBC cancels your show after 3 seasons,” as Mayan synced her lips to an audio clip of somebody saying, “That was rude. That was pretty f–king rude.”

“We will definitely put something out officially… for now. I would really love to thank all of you who have showed us so much love and support for the past three seasons,” George said.

NBC canceled “Lopez vs. Lopez” after three seasons. Elizabeth Morris/NBC

“This wasn’t just a show, it was and is our lives. We created a family. We created jobs for RAZA, there is so much more that goes on behind the scenes and I am forever grateful and thankful for every single member of our #LopezVSLopez familia.”

George, Mayan, and Debby Wolfe created the comedy about a dysfunctional working-class family.

George and Mayan played a fictionalized version of themselves in the series alongside Matt Shively, Brice Gonzalez, Selenis Leyva and Al Madrigal.

George Lopez and his daughter, Mayan, played fictionalized versions of themselves in the comedy. Elizabeth Morris/NBC

George and Mayan were estranged for nearly a decade before the show. Chris Pizzello/Invision/AP

The final episode aired in early February.

The comedy, which debuted in 2022, had low ratings during its run on NBC, TV Series Finale reported.

The third season of the show dipped by 18% in the 18-49 demographic compared to season two, according to the data reviewed by the outlet.

The comedian teased potentially retiring when he went on “The Jennifer Hudson Show” in February.

The comedian discussed retiring during an appearance on “The Jennifer Hudson Show” in February. Getty Images

Mayan, who doesn’t have many acting credits aside from “Lopez vs. Lopez,” claimed that this is “just the beginning.”

“There’s so much to say, and I’ll say more after today, but it was my biggest dream to be on NBC and to be a Latina lead for three seasons, will forever be the crown achievement of my career,” Mayan wrote on Instagram.

George and Mayan before the younger Lopez posted a TikTok about her family dynamic as they reconnected and sparked the idea for the show.

“I posted a TikTok five years ago and @debbywolfe and @georgelopez we made magic. I’ll always be grateful that you saw our vulnerability as a strength and made an incredible sitcom Debby.

“I’ll say a more heartfelt post, but I think the entire casting crew who are now my family for. Thank you all who have reached out to me and especially the fans who have watched and loved the show as much as I loved making it. It is the Lopez way that we will not be down for long.”

NBC canceled several programs on Friday, including “Suits LA,” “Night Court,” “The Irrational,” and “Found” as it prepares to make room for the with the NBA and WNBA starting in the 2025-2026 season.